Biocidal Activity Of Six Medicinal Plants In The Municipality Of Tacaná, San Marcos, Guatemala
DOI:
https://doi.org/10.54495/Rev.Cientifica.EdicionEspecial2005.195Keywords:
Biocidal activity, Plants for medicinal use, Tacana MunicipalityAbstract
In the municipality of Tacaná. San Marcos, Cardona in 2001 he began a thesis work in which he collected ethnobotanical information from the Mam community. The results of this work were proposed as a recommendation for the scientific validation of the therapeutic action attributed to plants, especially those that have little or no bibliographic information. Six species were selected and obtained: Bocconia arborea, Hypericum idiginosum, Prionosciadium lhapsoides, Salvia lavanduloides, Salvia microphylla and Selaginella silvestris and the components related to 95% ethanol of each one were extracted by repercolation.
The ethanolic extracts were confronted with Gram positive and Gram negative bacteria, yeasts, filamentous fungi, protozoa, insect larvae and the nauplius Anemia salina, in order to determine their biocidal activity.
In the antibacterial and antiyeast assay, the activity of H. idiginosum was demonstrated at a minimum inhibitory concentration (MIC) of 0.25 mg/mL for Staphylococcus aureus, Bacillus subtilis, Mycobacterium smegmatis and Cryptococcus neoformans, and at a MIC of 1 mg/mL for Trichophyton rubrum', S. microphvlla had activity at an MIC of 0.25 mg/mL for C. neoformans, 0.5 mg/mL for S. atireus, B. subtilis, M. smegmatis, and 1 mg/mL for T rubrum', from B arboreal a MIC of 0.5 mg/mL sc found activity against S. aureus and M. smegmatis; for P lhapsoids at a MIC of 0.5 mg/mL for M. smegmatis and T. rubrum at a MIC of 1 mg/mL; 5', lavanduloides for 5. aureus, B. subtilis, M. smegmatis, C. neoformans at an MIC of 1 mg/mL. No activity was found in S. silvestris.
In the activity against protozoa, a biocidal effect was found in B. arborea, inhibiting 90% of the protozoa at the following concentrations: 0.38 mg/mL for Trypanosoma cruzi, 0.46 mg/mL for Leishmania braziliensis and 0.82 mg/mL for Leishmania mexicana.
The ethanolic extract from the seed of P. lhapsoides inhibited the Leishmania genus at a concentration of 0.66 mg/mL and 0.79 mg/mL for L. braziliensis and L. mexicana, respectively.
No extract showed cytotoxic activity against A. salina, nor insecticidal activity against Aedes aegypti and Anopheles albimanus larvae in any of their four larval stages.
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Copyright (c) 2005 Lorde Lorenzana, Antulio Neliemías, Cardona Fuentes, Armando Cáceres
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