Anti-inflammatory activity of Gnaphalium Stramineum HBK (heal-all)
DOI:
https://doi.org/10.54495/Rev.Cientifica.v11i1.374Keywords:
anti-inflamatory activity, Gnaphalium Stramineum HBK (heal-all)Abstract
The present investigation was carried out with the purpose of evaluating the anti-inflammatory activity of extracts and eromatographic fractions of the flowers of the species Gnaphalium stramineum HBK (Sanalotodo) and to isolate the main active ingredient(s) responsible for said activity. The in vivo tests of anti-inflammatory activity and the phytochemical study carried out have allowed to isolate compounds derived from caffeoylquinic acid and flavonoid glycosides as the main active ingredients responsible for said pharmacological activity.
Downloads
References
Aquino R. et al. (1991) Plant metabolities. New compounds and ant-inflamatory activity of Uncaria Tomentosa. J. Nat. Prod. 54 (2). 453-459, https://doi.org/10.1021/np50074a016 DOI: https://doi.org/10.1021/np50074a016
Peluso G. el al. (1995) Studies on the inhibitory effects of caffeoylquinic acids on monocyte migration an superoxide ion production. J. Nat. Prod. 58 (5). 639-646, https://doi.org/10.1021/np50119a001 DOI: https://doi.org/10.1021/np50119a001
Kimura Y. et al, (1984) Studies on the activities of tannins and related compounds: V Inhibitory effects on lipid peroxidation in mitochondria and microsomes of liver. Planta Medica 50. 473-477, https://doi.org/10.1055/s-2007-969776 DOI: https://doi.org/10.1055/s-2007-969776
Kimura Y. et al. (1985) Studies on the activities of tannins an related comopounds from medicinal plants and drugs. VI. Inhibitory effects of caffeoylquinic acids on the histamine release from rat peritoneal mast cells. Chem. Pharm. Bull. 33 (2). 660-666, https://doi.org/10.1248/cpb.33.690 DOI: https://doi.org/10.1248/cpb.33.690
Kumura et al. (1987). Studies on the activities of tannins and related compounds. X. Effects of caffeetannins and related compounds on arachidonate metabolism in human polymorphonuclear leukocytes. J. Nat. Prod. 50, 397, https://doi.org/10.1021/np50051a009 DOI: https://doi.org/10.1021/np50051a009
Moroney M. (1988) Selectivity of neutrophil 5-lipoxigenase and ciclooxygenase inhibitor by an anti-inflamatory flavonoid glycoside and related flavonoids. J Pharm. Pharmacol. 40. 787, https://doi.org/10.1111/j.2042-7158.1988.tb05173.x DOI: https://doi.org/10.1111/j.2042-7158.1988.tb05173.x
Amellal M. et al. (1985). Inhibition of mast cell histamine release by flavonoids an biflavonoids. Planta Médica . 16-20, https://doi.org/10.1055/s-2007-969381 DOI: https://doi.org/10.1055/s-2007-969381
Timmerman B. et al. (1983) Constituents of Chrysotamnus paniculatus 3.4,5-tricaffeoylquinic acid (a new shikimate prearomatic) a n d 3.4-. 3, 5- and 4,5-dicaffeoylquinicacids. J. Nat Prod. 46 (3), 365-368, https://doi.org/10.1021/np50027a012 DOI: https://doi.org/10.1021/np50027a012
Rastrelli L, et al. Studies on the constituents of Chenopodium pallidicaule (Cañihua) seeds. Isolation and charcterization of two new flavonol glycosides. J. Agrie, food Chem. 43 (8). 2020-2024, https://doi.org/10.1021/jf00056a012 DOI: https://doi.org/10.1021/jf00056a012
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 1996 L Rastelli, M Hernández, A Saravia, L Madariaga, F De Simone
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4.0 that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
