Incidence of hepatitis B in at-risk personnel
DOI:
https://doi.org/10.54495/Rev.Cientifica.v12i1.342Keywords:
incidence, hepatitis B, at-risk personnelAbstract
In order to establish the incidence of hepatitis B in at-risk personnel, a serological study was carried out among 325 health workers at the San Juan de Dios General Hospital in Guatemala; in which the following markers were evaluated: Hepatitis B Surface Antigen (HBsAg), Antibody against the Surface Antigen (Anti-HBsAg), and Antibody against the Central Antigen (Anti-Core).
We used in our study the techniques of: Multienzymatic Solid Phase Assay ELISA, according to the Behring Enzygnost and SERODIA Passive Hemagglutination methods. Taking as positive all those cases in which at least one of the three serological markers evaluated was found.
We included in the study different areas of work, as well as different professions and trades, in order to determine those with the highest risk of infection with the hepatitis B virus. In addition, a survey was conducted on all people included in the study. in which various aspects were evaluated, which allow us to determine whether the incidence found can be attributed to work factors (work areas, frequency and type of work accidents, risky practices, etc.), or to other causes unrelated to their profession (IV drugs, transfusions). previous blood tests, HB vaccines, tattoos, etc.). We obtained a total of 40 positive cases (12.31%) from the studied population, which revealed the following:
0 cases of HBsAg (no cases of acute hepatitis B or asymptomatic chronic carrier state).
32 cases of Anti-HBsAg and Anti-Core (pre-infection followed by immunization by antibody production).
1 case only Anti-HBsAg (due to previous immunization with vaccine).
7 cases only Anti-Core (previous infection in which Anti-HBsAg has already disappeared, or window period”, in which HBsAg is no longer detected and there is still no Anti-HBsAg) (1).
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Copyright (c) 1999 Silvia Eugenia Soto Cordón, Julio Cáceres, Jorge R. Pérez Folgar
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