Changes in serum lipid levels during contraceptive administration
DOI:
https://doi.org/10.54495/Rev.Cientifica.v1i1.482Keywords:
changes, serum lipid levels, contraceptive administrationAbstract
Due to the widespread use of estrogens and progestins as contraceptives and the numerous reports associating them with changes in lipid metabolism, the present study was conducted to determine the changes that three different contraceptives cause in the lipid and lipoprotein levels of women who use them as contraceptives. Serum lipids and lipoproteins were determined in 103 women undergoing different contraceptive methods. Thirty women who do not use oral or injected contraceptives were chosen as the normal reference population, and 73 women who have used them for a time interval ranging from 9 months to 9 years were chosen as the sample. The relative frequency of the concentration values (in mg/dl) obtained in the different determinations performed are higher for the samples than for the normal population. Statistical analysis for the Student t test of the populations allowed us to conclude that the results obtained are statistically significant at a confidence level of 0.05. Marked hypertriglyceridemia with decreased high-density lipoprotein (HDL) cholesterol fractions is observed, which is significant for the purposes of this study. It should be noted that long-acting contraceptives (trimester-monthly injections) cause an elevation in serum lipids as great as that of combined oral contraceptives and once-daily oral contraceptives. The degree of hyperlipidemia depends on the type of contraceptive used. Decreased HDL cholesterol levels and elevated low-density and very-low-density lipoproteins (LDL and VLDL) increase the risk of hypercholesterolemia and the tendency toward vascular disorders.
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Copyright (c) 1983 Alma Marina Dávila, Alba Marina Valdés de García
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