Niveles de hierro sérico y predisposición a la adquisición de una candidosis producida por Candida albicans

Paula Castellanos Fernández; Heidi de Toledo

doi:10.54495/Rev.Cientifica.v3i1.463

Authors

Paula Castellanos Fernández Faculty of Chemical Sciences and Pharmacy
Heidi de Toledo Department of Microbiology

DOI:

https://doi.org/10.54495/Rev.Cientifica.v3i1.463

Keywords:

serum iron levels, predisposition, candidiasis , Candida albicans

Abstract

Currently, the predisposition to acquiring infections caused by opportunistic microorganisms is of great importance. This research demonstrated the relationship between infection caused by the yeast-like fungus Candida albicans and one of the predisposing factors for candidiasis: low serum iron levels.

One hundred ninety patients were studied, divided into 127 pregnant women and 63 newborns. The proportion of sick and healthy groups undergoing serum iron analysis for each population was 34:43 and 30:26, respectively. Statistical analysis of the results using the F and t tests demonstrated heterogeneity and differences in serum iron concentrations between the healthy and sick groups, respectively. This confirms the hypothesis and leads to the conclusion that iron can be used to prevent infection by this fungus.

The above suggests the use of this element as a treatment for infections caused by C. albicans, since the recovery of a newborn patient was demonstrated, whose only treatment consisted of adequate doses of ferrous sulfate.

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