Production of albumin nano-colloid radiopharmaceutical labeled with 99mTC for scintigraphic studies of the lymphatic system and bone marrow

Authors

  • Alba Evelia González Alvarado de Torres Pharmaceutical Chemistry
  • Claudia María Quintero Jordán Biological Chemistry. Radiopharmacy, General Directorate of Nuclear Energy

DOI:

https://doi.org/10.54495/Rev.Cientifica.v13i1.327

Keywords:

albumin nanocolloid radio-pharmaceutical, 99mTC, scintigraphic studies, lymphatic system, bone marrow

Abstract

The purpose of this work was to produce a new radiopharmaceutical for the detection of cancer, quality control through radiochemical purity, microbiological control and organoleptic quality, evaluate the biodistribution in rats and verify its stability.   The drug NANO-ALBUMIN COLLOID was labeled with 99mTc. Biodistribution was evaluated in albino rats and the results were subjected to one-way analysis of variance and multiple comparisons.

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References

Jánoki GA. Documento Técnico. "Frédérid Jdiot-Curie: National Research Institute for Radiobiology and Radiohygtiene. Budapest, Hungary 1957. Producción de Nano-coloide. 1992.

Mitta A. Valor de la Linforentellografía en el Cáncer de Mama. Acta Bioquímica Clínica Latinoamericana, vol XXVIII, No. 1, 117-124, 1989. (p. 11 7-1 23).

Valenzuela H, et al. Utilidad de la Gammagrafla Medular con Nanocoloides como complemento de la Gammagrafla ósea en Cáncer de Mama Rev. Esp. Med. Nud. 1995; XIV:3

Brobeck J. Bases Fisiológicas de la Práctica Médica. 10a Ed. México: Médica Panamericana. 1982. (p. 726- 733)

George G. Medicina Intema 5ta. Ed. en español. Científicas. La Prensa Médica Mexicana. México 1984. Tomo II Cap. 252 p.1575-1 576; Tomo I Cap. 62 p. 353; Tomo II Cap. 311 p. 1979-1987,

Saha GB. Fundamentals of Nuclear Pharmacy. 3rd. Ed. 1992 USA Springer-Verlaq (p.273-275).

https://doi.org/10.1007/978-1-4757-4027-1 DOI: https://doi.org/10.1007/978-1-4757-4027-1

Mallol Escobar J. Radiofarmacia. Ed. Interamericana-Mc Graw Hill Madrid 1989. p. 41

Horiuchi K, et a! Tc(v)-DMS tumor imaging agent; Te complexes dissociation equilibria a relevant factor in tumor localization. Technetium in Chemister and Nuclear Medicine 2. NY. Cortina International-Verona Raven Press. 1980. p. 155-159

The United States Pharmacopeia. Twenty-first Revision Offi cial from January 1, 1985. The National Formulary sixteenth Edition. USPXX1. p. 1279-1282

Farmacopea de los Estados Unidos Mejicanos. 5ta. Ed Secretaria de Salud. Comisión Permanente de la Farmacopea de los Estados Unidos Mejicanos. México 1988. p.60-61

Published

2000-12-31

How to Cite

González Alvarado de Torres, A. E., & Quintero Jordán, C. M. (2000). Production of albumin nano-colloid radiopharmaceutical labeled with 99mTC for scintigraphic studies of the lymphatic system and bone marrow. Revista Científica, 13(1), 7–10. https://doi.org/10.54495/Rev.Cientifica.v13i1.327

Issue

Section

Original Research Papers

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