Serum iron levels and predisposition to acquiring candidiasis caused by Candida albicans
DOI:
https://doi.org/10.54495/Rev.Cientifica.v3i1.463Keywords:
serum iron levels, predisposition, candidiasis , Candida albicansAbstract
Currently, the predisposition to acquiring infections caused by opportunistic microorganisms is of great importance. This research demonstrated the relationship between infection caused by the yeast-like fungus Candida albicans and one of the predisposing factors for candidiasis: low serum iron levels. One hundred ninety patients were studied, divided into 127 pregnant women and 63 newborns. The proportion of sick and healthy groups undergoing serum iron analysis for each population was 34:43 and 30:26, respectively. Statistical analysis of the results using the F and t tests demonstrated heterogeneity and differences in serum iron concentrations between the healthy and sick groups, respectively. This confirms the hypothesis and leads to the conclusion that iron can be used to prevent infection by this fungus. The above suggests the use of this element as a treatment for infections caused by C. albicans, since the recovery of a newborn patient was demonstrated, whose only treatment consisted of adequate doses of ferrous sulfate.
Downloads
References
González A. Relación Huésped-Parásito en las Infecciones por Candida. Gac Med Mex. 1975; 109(2) :115.
Anónimo. Complementary Effects of Fever and Low Iron on Defence against Bacterial Infection. Nutr Rev 1979; 37(8) :260-261. https://doi.org/10.1111/j.1753-4887.1979.tb06684.x DOI: https://doi.org/10.1111/j.1753-4887.1979.tb06684.x
Drouhet E. Les Candidoses et leur Diagnostic de Laboratoire. Francia:Lab Squibb Pain, 1965. (p. 5,39-40).
Segretain G, Drouhet E, Mariat F. Diagnóstico de Laboratorio en Micología Médica. Macotela E, trad. México: La Prensa Médica Mexicana, 1966. (p. 113).
Davis B, et al. Tratado de Microbiología con Inclusión de Inmunología y Genética Molecular. 2 ed. Egozcue J, trad. España: Salvat, 197,8. (p. 993).
Balish E. C h lamydospore Production and Germ-tube Formation by Auxotrophs of Candida albicans. Appl Microbiol 1973; 25(4) :615-620. https://doi.org/10.1128/am.25.4.615-620.1973 DOI: https://doi.org/10.1128/am.25.4.615-620.1973
Emmons C, et al. Medical Mycology. London: Henry Kimpton Publishers, 1963. (p. 131).
Lewis G, Hopper M. An Introduction to Medical Mycology. 3 ed. USA : The Year Book Publishers, 1948. (p. 146). https://doi.org/10.5962/bhl.title.7443 DOI: https://doi.org/10.5962/bhl.title.7443
Murillo de Linares L, Marín C. Frequency of Yeasts of the Genus Candida in Humans, as Pathogens and as Part of Normal Flora, p. 124. (In Proceedings of the Fourth International Conference on the Mycoses. The Black and White Yeasts. USA: Pan American Health Organization, 1978).
Padilha-Goncalves A. Current Aspects of Mucocutaneous Candidiasis. p. 135-137. (In Proceedings of the Fourth International Conference on the Mycoses. The Black and White Yeasts. USA: Pan American Health Organization, 1978).
Fischer J, Cañe J. Production of Chlamydospores by Candida albicans Cultivated on Dilute Oxgall Agar. Mycopathol et Mycol Appl 1968;35 (3-4) :223-229. https://doi.org/10.1007/BF02050734 DOI: https://doi.org/10.1007/BF02050734
Taschdjian C, Burchall J, Kozinn P. Rapid Identification of Candida albicans by Filamentation on Serum and Serum Substitutos. J Dis Child 1960; 9:102-105.
Kamaya T. Simple Rapid Identification of Gandida albicans with Emphasis on the Differentiation between Candida albicans and Candida Stellatoidea. Mycopath et Mycol Appl 1968; 35(2) :105-112. DOI: https://doi.org/10.1007/BF02049573
Bóehringer-Mannheim, División Diagnóstica. Test-Combination. Hierro sin Desproteinización. Instrucciones de Trabajo. Línea Diagnóstico-Terapéutica. Guatemala: CGFIA, 1982. (Original sin paginación).
Calzada J. Métodos Estadísticos para la Investigación. 3 ed. Perú: Jurídica, 1970. (p. 73-74, 77).
Anónimo. Biblioteca de Programas FX-702P. Japón: Casio Computer, 1982. (p. 105-106).
Anónimo. Manual de Instrucciones. Calculadora Programa ble Casio FX-702P. Japón: Casio Computer, 1982. (p. 71-72).
Spiegel M.Probabilidad y Estadística. Ozuna J, trad. México: McGraw-Hill, 1976. (p. 348).
Steel R, Torrie J. Principies and Procedures of Statistics with Special Reference to the Biological Sciences. New York: McGraw-Hill Book Company, 1960. (p. 433).
Duncan R, Artis W. Fungistatic Capacity of Sera from Guinea Pigs Injected with various Iron Solutions: Differences between Trichophyton mentagrophytes and Rhizopus oryzae. Infect Immun 1982; 35(1) :368-370. https://doi.org/10.1128/iai.35.1.368-370.1982 DOI: https://doi.org/10.1128/iai.35.1.368-370.1982
Hendry A, Bakerspigel A. Factors Affecting Serum Inhibited Growth of Candida albicans and Cryptococcus neoformans. SABOURAUDIA 1970; 7:219-229. https://doi.org/10.1080/00362177085190391 DOI: https://doi.org/10.1080/00362177085190391
Castellanos P. Niveles de Hierro Sérico y Predisposición a la Adquisición de una Candidosis producida por Candida albicans. Guatemala: Universidad de San Carlos, (Tesis de Graduación, Facultad de Ciencias Químicas y Farmacia) 1984. 154p. (p. 81-87).
Chang L, Chúa K, Yong Y, Sivasamboo R. Haematological Differences between the Blood of Mothers and their Newborn Infants. Singapore Med J 1972; 13(6) :280-283. Chem Absts 1973; 78:145720e.
Tietz N, et al. Química Clínica Moderna. Toral M, .rad. México: Interamericana, 1972. (p. 680).
Levi L. Definition and Evaluation of Stress. Govt Rep Announce 1972; 72(4) :46. Chem Absts 1972; 77:3370w.
Rath C, Finch C. Chemical, Clinical, and Immunologícal Studies on the Products of Human Fractionation. XXXVIII. Serum Iron Transport. Measurement of Iron-Binding Capacity of Serum in Man. J Clin Invest 1949; 28:84. https://doi.org/10.1172/JCI102057 DOI: https://doi.org/10.1172/JCI102057
Robinson S, Tasker S. Chronic Latent Oral Moniliasis (Thrush). Report of a Case of Twelve years, Duration in wich the Disease was Resistant to Treatment. Arch Dermat Syph 1947; 55:85-90. https://doi.org/10.1001/archderm.1947.01520010089009 DOI: https://doi.org/10.1001/archderm.1947.01520010089009
Baños J. Candidiasis Mucocutánea Crónica en Niños. Tratamiento con Ketoconazole. p. 38. (En Resúmenes del XIII Congreso Centroamericano de Dermatología.'Guatemala: Academia Guatemalteca de Dermatología, Sifilología y Leprología, 1982).
Downloads
Published
Issue
Section
License
Copyright (c) 1985 Paula Castellanos Fernández, Heidi de Toledo
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4.0 that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
How to Cite
